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Clinically Relevant Molecular Biology M B Agarwal
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Molecular tests are useful for diagnosis, prognosis and treatment of haematological malignancies.The various molecular technologies include FISH,polymerase chain reaction, next generation sequencing etc. Today, we are movingtowards personalisedcancer therapy based on molecular profiling and prognostic markers predictive of drugsensitivity/resistance and adverse events.In this presentation, noted haematologist,Dr. M.B.Agarwal discusses the clinically relevant molecular biology inleukaemia, lymphoma and myeloma.

The various mutations inmyeloproliferative neoplasmsviz.Bcr-abl, JAK2, CAL R, MPL, CSF 3Rareexplainedin detail.Dr. Agarwalgives an overview ofthe molecular biology and testing in various MPNs such aschronic myeloid leukemia, polycythemiavera, essential thrombocythemia and primary myelofibrosis.

The presentation also includes themolecular biology and testinginmyelodysplastic syndrome, paediatricacute lymphoblastic leukemia, adultB cellacute lymphoblasticleukemia, T cellacute lymphoblasticleukemia,Waldenstromm macroglobulinemia and myeloma.

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