The ombophilia is defined as a venous thrombosis with a detectable abnormality in blood. It is important to know a thrombophilic state to prevent recurrence, plan duration of anticoagulation, give prophylaxis in high risk situations and pick up family members at risk.
Eminent haematologist Dr. M.B. Agarwal discusses the pathophysiology and clinical presentation of venous thromboembolism, deep vein thrombosis and pulmonary embolism. The causes, risk factors, tests and the guidelines for testing for thrombophilia are included. It is important to use the right anticoagulant and test at the right time. Antiphospholipid antibody syndrome is an autoimmune disorder characterized by thrombosis, foetal wastage and immune thrombocytopenia. The clinical presentation, laboratory testing of APLA syndrome is discussed at length.
1. Head, Department of Haematology, Bombay Hospital Institute of Medical Sciences, Mumbai 2. Director : Haematology Centre at Ghamat Lodge, 804-A, Dr. B. Ambedkar Road, Dadar TT, Mumbai - 400 014, India 3. Consultant Haematologist * Lilavati Hospital, Mumbai * Breach Candy Hospital, Mumbai. * BARC Hospital, Trombay, Mumbai * RCF Hospital, Chembur, Mumbai * Larsen & Toubro, Mumbai 4. Past President: Indian Society of Haematology and Transfusion Medicine 08-09 5. President: Mumbai Haematology Group, 2008-10 6. Ex-Professor, Division of Haematology, Dept. of Medicine, L.T.M.G. Hospital & L.T.M. Medical College, Sion, Mumbai - 400 022 (Retired)